Jaya T. Venkatraman, PhD, CNS, FACN, Xiaohong Feng, MS, and David Pendergast, EdD
Department of Physical Therapy, Exercise and Nutrition Sciences (J.T.V., X.F.), Department of Physiology (D.P.), State University of New York at Buffalo, Buffalo, New York [jtv@acsu.buffalo.edu]
Objective: Exercise and the neuroendocrine and oxidative stress it elicits on immune function is modulated by dietary fat intake. The effects of increasing dietary fat on endurance exercise-induced alterations (80% of VO2max for 2 hours) in the plasma levels of cortisol and prostaglandin E2 (PGE2), interferon-gamma (IFN-gamma) and lipid peroxides were investigated. As higher levels of cortisol, PGE2 and lipid peroxides could be immunosuppressive, the effects of different levels of dietary fat on these measures in runners were determined. Continue reading